The American Women's Club of Central Scotland is a social club established to enable American women to meet other Americans living in the area. Its purpose is to promote intellectual, social, and charitable contacts by and for Americans and their families living in Central Scotland.

The origins of the AWCCS go back to the early 1970s, when the wives of employees at Santa Fe, a supply company for the off-shore oil industry, began to hold informal lunchtime gatherings. Other American women in Edinburgh were soon attracted to their meetings, and in 1974 the American Women's Club of Edinburgh was formally established and by-laws drawn up. In May 1998 the American Women's Club of Edinburgh became the American Women's Club of Central Scotland: Edinburgh, Central Region, Glasgow.